人 TAF2 (NM_003184) cDNA克隆

Accession: NM_003184
基因名称: TAF2
基因别名: TAF2B; CIF150; TAFII150
基因描述: Homo sapiens TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa (TAF2), mRNA.
种属: Human
CDS区长度: 3600 (查看编码区序列)
翻译后氨基酸长度: 1199 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G170185 人 TAF2 (NM_003184) cDNA克隆 pDONR223 2ug质粒 点击询价

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators. [provided by RefSeq, Jul 2008]