人 TRRAP (NM_003496) cDNA克隆

Accession: NM_003496
基因名称: TRRAP
基因别名: Tra1; TR-AP; PAF400; STAF40; PAF350/400
基因描述: Homo sapiens transformation/transcription domain-associated protein (TRRAP), transcript variant 2, mRNA.
种属: Human
CDS区长度: 11493 (查看编码区序列)
翻译后氨基酸长度: 3830 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon and uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
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G170436 人 TRRAP (NM_003496) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]