人 SCARF2 (NM_182895) cDNA克隆

Accession: NM_182895
基因名称: SCARF2
基因别名: NSR1; SREC2; VDEGS; SREC-II; SRECRP-1
基因描述: Homo sapiens scavenger receptor class F, member 2 (SCARF2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2598 (查看编码区序列)
翻译后氨基酸长度: 865 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame segment within the coding region, as compared to variant 1. The resulting isoform (2) lacks an internal region, as compared to isoform 1.
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G170501 人 SCARF2 (NM_182895) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]