人 SLC4A7 (NM_001258379) cDNA克隆

Accession: NM_001258379
基因名称: SLC4A7
基因别名: NBC2; NBC3; SBC2; NBCN1; SLC4A6
基因描述: Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 7 (SLC4A7), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3396 (查看编码区序列)
翻译后氨基酸长度: 1131 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant has additional differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a.
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G170536 人 SLC4A7 (NM_001258379) cDNA克隆 pDONR223 2ug质粒 点击询价

This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]