人 DLEC1 (NM_007337) cDNA克隆

Accession: NM_007337
基因名称: DLEC1
基因别名: F56; DLC1
基因描述: Homo sapiens deleted in lung and esophageal cancer 1 (DLEC1), transcript variant DLEC1-S3, mRNA.
种属: Human
CDS区长度: 5337 (查看编码区序列)
翻译后氨基酸长度: 1778 (查看氨基酸序列)
Transcript Variant: This variant (DLEC1-S3) lacks an exon in the 3' coding region that results in a frameshift and use of a downstream stop codon, compared to variant DLEC1-N1. The encoded isoform (DLEC1-S3) has a longer, distinct C-terminus compared to the DLEC1-N1 isoform. There are currently no publicly available full-length transcripts supporting this variant, but it is supported by data in PMID:10213508.
产品编号 产品名称 载体 规格 价格
G170555 人 DLEC1 (NM_007337) cDNA克隆 pDONR223 2ug质粒 点击询价
人 DLEC1 (NM_007335) cDNA克隆 transcript variant DLEC1-N1
人 DLEC1 (NM_007337) cDNA克隆 transcript variant DLEC1-S3

This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney. [provided by RefSeq, Jul 2008]