人 CDRT1 (NM_001282540) cDNA克隆

Accession: NM_001282540
基因名称: CDRT1
基因别名: HREP; SM25H2; C170RF1; C17ORF1; FBXW10B; C17ORF1A; FBXW10P1
基因描述: Homo sapiens CMT1A duplicated region transcript 1 (CDRT1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2145 (查看编码区序列)
翻译后氨基酸长度: 714 (查看氨基酸序列)
Transcript Variant: This variant (2) has alternate 3' exon structure and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (b) has a distinct and shorter C-terminus, compared to isoform a.
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G172071 人 CDRT1 (NM_001282540) cDNA克隆 pDONR223 2ug质粒 点击询价

Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]