人 CTBP2 (NM_001329) cDNA克隆

基本信息

Accession: NM_001329
基因名称: CTBP2
基因描述: Homo sapiens C-terminal binding protein 2 (CTBP2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1338 (查看编码区序列)
翻译后氨基酸长度: 445 (查看氨基酸序列)
Transcript Variant: This variant (1) contains a distinct 5' UTR and 5' CDS, compared to variant 2. Both variants 1 and 3 encode the same isoform (1), which has a distinct N-terminus that is 540 aa shorter than the N-terminus of isoform 2. The protein is thought to bind to the C-terminus of the adenovirus E1A proteins. Studies in mice suggest that this protein is involved in transcriptional repression.

订购信息

产品编号 产品名称 载体 规格 价格
G101960 人 CTBP2 (NM_001329) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CTBP2 (NM_001329) cDNA克隆 transcript variant 1
人 CTBP2 (NM_022802) cDNA克隆 transcript variant 2
人 CTBP2 (NM_001083914) cDNA克隆 transcript variant 3

基因简介

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. [provided by RefSeq, Jul 2008]

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