人 CTBP2 (NM_022802) cDNA克隆

Accession: NM_022802
基因名称: CTBP2
基因描述: Homo sapiens C-terminal binding protein 2 (CTBP2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2958 (查看编码区序列)
翻译后氨基酸长度: 985 (查看氨基酸序列)
Transcript Variant: This variant (2) represents the longest transcript and encodes the longer isoform (2). This protein localizes to synaptic ribbons, synapses used for fast tonic neurotransmitter release in a subset of specialized neurons.
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G101961 人 CTBP2 (NM_022802) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. [provided by RefSeq, Jul 2008]