人 NCOA4 (NM_001145261) cDNA克隆

Accession: NM_001145261
基因名称: NCOA4
基因别名: RFG; ELE1; PTC3; ARA70
基因描述: Homo sapiens nuclear receptor coactivator 4 (NCOA4), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1893 (查看编码区序列)
翻译后氨基酸长度: 630 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon in the coding region, which results in a frameshift and use of a downstream stop codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1.
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G102296 人 NCOA4 (NM_001145261) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. [provided by RefSeq, Feb 2009]