人 CLEC7A (NM_197947) cDNA克隆

Accession: NM_197947
基因名称: CLEC7A
基因别名: BGR; CANDF4; DECTIN1; CLECSF12
基因描述: Homo sapiens C-type lectin domain family 7, member A (CLEC7A), transcript variant 1, mRNA.
种属: Human
CDS区长度: 744 (查看编码区序列)
翻译后氨基酸长度: 247 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variant 1 has been alternatively referred to as variant 2 and isoform a has been alternatively referred to as alpha in the literature.
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G102720 人 CLEC7A (NM_197947) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]