人 CLEC7A (NM_197949) cDNA克隆

基本信息

Accession: NM_197949
基因名称: CLEC7A
基因别名: BGR; CANDF4; DECTIN1; CLECSF12
基因描述: Homo sapiens C-type lectin domain family 7, member A (CLEC7A), transcript variant 4, mRNA.
种属: Human
CDS区长度: 432 (查看编码区序列)
翻译后氨基酸长度: 143 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks two alternate exons, which results in a frameshift and an early stop codon, compared to variant 1. The resulting protein (isoform d) is shorter and contains a distinct C-terminus, compared to isoform a. Isoform d has been alternatively referred to as 'c' in the literature.

订购信息

产品编号 产品名称 载体 规格 价格
G102722 人 CLEC7A (NM_197949) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CLEC7A (NM_197947) cDNA克隆 transcript variant 1
人 CLEC7A (NM_022570) cDNA克隆 transcript variant 2
人 CLEC7A (NM_197948) cDNA克隆 transcript variant 3
人 CLEC7A (NM_197949) cDNA克隆 transcript variant 4
人 CLEC7A (NM_197950) cDNA克隆 transcript variant 5
人 CLEC7A (NM_197954) cDNA克隆 transcript variant 6

基因简介

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]

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