人 BANF1 (NM_003860) cDNA克隆

Accession: NM_003860
基因名称: BANF1
基因别名: BAF; NGPS; BCRP1; D14S1460
基因描述: Homo sapiens barrier to autointegration factor 1 (BANF1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 270 (查看编码区序列)
翻译后氨基酸长度: 89 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
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G102781 人 BANF1 (NM_003860) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Jan 2009]