人 GADD45A (NM_001924) cDNA克隆

Accession: NM_001924
基因名称: GADD45A
基因别名: DDIT1; GADD45
基因描述: Homo sapiens growth arrest and DNA-damage-inducible, alpha (GADD45A), transcript variant 1, mRNA.
种属: Human
CDS区长度: 498 (查看编码区序列)
翻译后氨基酸长度: 165 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G103217 人 GADD45A (NM_001924) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010]