人 GADD45A (NM_001199742) cDNA克隆

基本信息

Accession: NM_001199742
基因名称: GADD45A
基因别名: DDIT1; GADD45
基因描述: Homo sapiens growth arrest and DNA-damage-inducible, alpha (GADD45A), transcript variant 3, mRNA.
种属: Human
CDS区长度: 183 (查看编码区序列)
翻译后氨基酸长度: 60 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks a coding exon, as compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G103219 人 GADD45A (NM_001199742) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GADD45A (NM_001924) cDNA克隆 transcript variant 1
人 GADD45A (NM_001199741) cDNA克隆 transcript variant 2
人 GADD45A (NM_001199742) cDNA克隆 transcript variant 3

基因简介

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010]

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