人 CFL2 (NM_021914) cDNA克隆

基本信息

Accession: NM_021914
基因名称: CFL2
基因别名: NEM7
基因描述: Homo sapiens cofilin 2 (muscle) (CFL2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 501 (查看编码区序列)
翻译后氨基酸长度: 166 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR and uses an alternate translational start codon, compared to variant 2, but the encoded isoform (1) is identical to that encoded by variant 2.

订购信息

产品编号 产品名称 载体 规格 价格
G103222 人 CFL2 (NM_021914) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CFL2 (NM_021914) cDNA克隆 transcript variant 1
人 CFL2 (NM_138638) cDNA克隆 transcript variant 2
人 CFL2 (NM_001243645) cDNA克隆 transcript variant 5

基因简介

This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

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