人 CFL2 (NM_001243645) cDNA克隆

基本信息

Accession: NM_001243645
基因名称: CFL2
基因别名: NEM7
基因描述: Homo sapiens cofilin 2 (muscle) (CFL2), transcript variant 5, mRNA.
种属: Human
CDS区长度: 450 (查看编码区序列)
翻译后氨基酸长度: 149 (查看氨基酸序列)
Transcript Variant: This variant (5) differs in the 5' UTR and uses a downstream, in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G103224 人 CFL2 (NM_001243645) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CFL2 (NM_021914) cDNA克隆 transcript variant 1
人 CFL2 (NM_138638) cDNA克隆 transcript variant 2
人 CFL2 (NM_001243645) cDNA克隆 transcript variant 5

基因简介

This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

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