人 CD99 (NM_001122898) cDNA克隆

Accession: NM_001122898
基因名称: CD99
基因别名: MIC2; HBA71; MIC2X; MIC2Y; MSK5X
基因描述: Homo sapiens CD99 molecule (CD99), transcript variant 2, mRNA.
种属: Human
CDS区长度: 510 (查看编码区序列)
翻译后氨基酸长度: 169 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
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G103317 人 CD99 (NM_001122898) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2013]