人 CD99 (NM_001277710) cDNA克隆

基本信息

Accession: NM_001277710
基因名称: CD99
基因别名: MIC2; HBA71; MIC2X; MIC2Y; MSK5X
基因描述: Homo sapiens CD99 molecule (CD99), transcript variant 3, mRNA.
种属: Human
CDS区长度: 483 (查看编码区序列)
翻译后氨基酸长度: 160 (查看氨基酸序列)
Transcript Variant: This variant (3, also known as type II) contains an alternate internal exon in the 3' end and uses an alternate splice junction in the penultimate exon compared to variant 1. The additional exon contains an in-frame stop codon, making the resulting isoform (c, also known as CD99sh) have a shorter and distinct C-terminus compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G103319 人 CD99 (NM_001277710) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CD99 (NM_002414) cDNA克隆 transcript variant 1
人 CD99 (NM_001122898) cDNA克隆 transcript variant 2
人 CD99 (NM_001277710) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2013]

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