人 MXD3 (NM_001142935) cDNA克隆

Accession: NM_001142935
基因名称: MXD3
基因别名: MYX; MAD3; BHLHC13
基因描述: Homo sapiens MAX dimerization protein 3 (MXD3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 582 (查看编码区序列)
翻译后氨基酸长度: 193 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 3' UTR and 3' coding region compared to variant 1. The resulting isoform (b) has a distinct C-terminus and is shorter than isoform a.
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G103429 人 MXD3 (NM_001142935) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]