人 MXD1 (NM_001202514) cDNA克隆

基本信息

Accession: NM_001202514
基因名称: MXD1
基因别名: MAD; MAD1; BHLHC58
基因描述: Homo sapiens MAX dimerization protein 1 (MXD1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 636 (查看编码区序列)
翻译后氨基酸长度: 211 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an exon in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G119701 人 MXD1 (NM_001202514) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MXD1 (NM_002357) cDNA克隆 transcript variant 1
人 MXD1 (NM_001202513) cDNA克隆 transcript variant 2
人 MXD1 (NM_001202514) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]

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