人 RGS20 (NM_001286675) cDNA克隆

Accession: NM_001286675
基因名称: RGS20
基因别名: RGSZ1; ZGAP1; gz-GAP; g(z)GAP
基因描述: Homo sapiens regulator of G-protein signaling 20 (RGS20), transcript variant 5, mRNA.
种属: Human
CDS区长度: 543 (查看编码区序列)
翻译后氨基酸长度: 180 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks two in-frame exons in the central coding region which results in the use of an alternate start codon compared to variant 1. The encoded isoform (e) is shorter than isoform a.
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G103493 人 RGS20 (NM_001286675) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]