人 RGS3 (NM_144489) cDNA克隆

基本信息

Accession: NM_144489
基因名称: RGS3
基因别名: C2PA; RGP3
基因描述: Homo sapiens regulator of G-protein signaling 3 (RGS3), transcript variant 5, mRNA.
种属: Human
CDS区长度: 936 (查看编码区序列)
翻译后氨基酸长度: 311 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks several 5' exons but includes an alternate 5' exon, and it thus differs in the 5' UTR, lacks a large portion of the 5' coding region, and uses an alternate start codon, compared to variant 6. The encoded isoform (5, also known as RGS3S in PubMed ID:12036301) has a significantly shorter and distinct N-terminus, compared to isoform 6.

订购信息

产品编号 产品名称 载体 规格 价格
G105244 人 RGS3 (NM_144489) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RGS3 (NM_130795) cDNA克隆 transcript variant 1
人 RGS3 (NM_001282923) cDNA克隆 transcript variant 10
人 RGS3 (NM_021106) cDNA克隆 transcript variant 2
人 RGS3 (NM_001282922) cDNA克隆 transcript variant 2
人 RGS3 (NM_017790) cDNA克隆 transcript variant 3
人 RGS3 (NM_134427) cDNA克隆 transcript variant 4
人 RGS3 (NM_144489) cDNA克隆 transcript variant 5
人 RGS3 (NM_144488) cDNA克隆 transcript variant 6
人 RGS3 (NM_001276260) cDNA克隆 transcript variant 7
人 RGS3 (NM_001276261) cDNA克隆 transcript variant 8
人 RGS3 (NM_001276262) cDNA克隆 transcript variant 9

基因简介

This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear. [provided by RefSeq, Jan 2013]

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