人 ING4 (NM_001127584) cDNA克隆

Accession: NM_001127584
基因名称: ING4
基因别名: my036; p29ING4
基因描述: Homo sapiens inhibitor of growth family, member 4 (ING4), transcript variant 4, mRNA.
种属: Human
CDS区长度: 738 (查看编码区序列)
翻译后氨基酸长度: 245 (查看氨基酸序列)
Transcript Variant: This variant (4) uses a different splice site in the coding region, compared to variant 9. The resulting protein (isoform 4) is shorter by 4 aa compared to isoform 9. Other names for this variant are ING4_v4 and "12 bp skip variant".
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G103643 人 ING4 (NM_001127584) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq, Jul 2008]