人 ING1 (NM_198217) cDNA克隆

Accession: NM_198217
基因名称: ING1
基因别名: p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a
基因描述: Homo sapiens inhibitor of growth family, member 1 (ING1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 708 (查看编码区序列)
翻译后氨基酸长度: 235 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' end-region, which includes part of the coding region, compared to variant 4. The resulting isoform (C) has a shorter N-terminus, as compared to isoform D.
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G150409 人 ING1 (NM_198217) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]