人 ICAM4 (NM_001544) cDNA克隆

Accession: NM_001544
基因名称: ICAM4
基因别名: LW; CD242
基因描述: Homo sapiens intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4), transcript variant 1, mRNA.
种属: Human
CDS区长度: 816 (查看编码区序列)
翻译后氨基酸长度: 271 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the full-length isoform (1) that contains 2 Ig-like C2-type domains, a single transmembrane domain, and a single cytoplasmic domain.
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G103728 人 ICAM4 (NM_001544) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]