人 ELAVL3 (NM_001420) cDNA克隆

Accession: NM_001420
基因名称: ELAVL3
基因别名: HUC; HUCL; PLE21
基因描述: Homo sapiens ELAV like neuron-specific RNA binding protein 3 (ELAVL3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1104 (查看编码区序列)
翻译后氨基酸长度: 367 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (1).
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G103853 人 ELAVL3 (NM_001420) cDNA克隆 pDONR223 2ug质粒 点击询价

A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]