A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
人 ELAVL3 (NM_032281) cDNA克隆
| Accession: | NM_032281 |
|---|---|
| 基因名称: | ELAVL3 |
| 基因别名: | HUC; HUCL; PLE21 |
| 基因描述: | Homo sapiens ELAV like neuron-specific RNA binding protein 3 (ELAVL3), transcript variant 2, mRNA. |
| 种属: | Human |
| CDS区长度: | 1083 (查看编码区序列) |
| 翻译后氨基酸长度: | 360 (查看氨基酸序列) |
| Transcript Variant: | This variant (2) lacks an in-frame segment in the coding region, as compared to variant 1. It encodes isoform 2 which lacks an internal segment, as compared to isoform 1. |
| 人 ELAVL3 (NM_001420) cDNA克隆 | transcript variant 1 |
| 人 ELAVL3 (NM_032281) cDNA克隆 | transcript variant 2 |
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