人 LSS (NM_001145436) cDNA克隆

Accession: NM_001145436
基因名称: LSS
基因别名: OSC
基因描述: Homo sapiens lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (LSS), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2166 (查看编码区序列)
翻译后氨基酸长度: 721 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region and has a different 3' UTR, compared to variant 2. These differences result in a shorter protein (isoform 2), compared to isoform 1.
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G104329 人 LSS (NM_001145436) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]