人 LSS (NM_001145437) cDNA克隆

基本信息

Accession: NM_001145437
基因名称: LSS
基因别名: OSC
基因描述: Homo sapiens lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (LSS), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1959 (查看编码区序列)
翻译后氨基酸长度: 652 (查看氨基酸序列)
Transcript Variant: This variant (4) retains an intron segment between exons 1 and 2, compared to variant 2. This difference introduces a premature stop codon and results in the use of a downstream, in-frame start codon. The encoded protein (isoform 3) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G104330 人 LSS (NM_001145437) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 LSS (NM_002340) cDNA克隆 transcript variant 1
人 LSS (NM_001001438) cDNA克隆 transcript variant 2
人 LSS (NM_001145436) cDNA克隆 transcript variant 3
人 LSS (NM_001145437) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]

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