人 CARS (NM_001014437) cDNA克隆

基本信息

Accession: NM_001014437
基因名称: CARS
基因别名: CARS1; CYSRS; MGC:11246
基因描述: Homo sapiens cysteinyl-tRNA synthetase (CARS), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2496 (查看编码区序列)
翻译后氨基酸长度: 831 (查看氨基酸序列)
Transcript Variant: This variant (3) includes an additional in-frame exon in the 5' coding region, and uses an alternate splice site that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (c) has an additional segment in the N-terminal region and a distinct and longer C-terminus, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G104337 人 CARS (NM_001014437) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CARS (NM_139273) cDNA克隆 transcript variant 1
人 CARS (NM_001751) cDNA克隆 transcript variant 2
人 CARS (NM_001014437) cDNA克隆 transcript variant 3
人 CARS (NM_001194997) cDNA克隆 transcript variant 5

基因简介

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]

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