人 CARS (NM_139273) cDNA克隆

Accession: NM_139273
基因名称: CARS
基因别名: CARS1; CYSRS; MGC:11246
基因描述: Homo sapiens cysteinyl-tRNA synthetase (CARS), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2181 (查看编码区序列)
翻译后氨基酸长度: 726 (查看氨基酸序列)
Transcript Variant: This variant (1) consists of 22 exons and encodes the shortest isoform (a).
产品编号 产品名称 载体 规格 价格
G104339 人 CARS (NM_139273) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]