人 CUL4B (NM_001079872) cDNA克隆

Accession: NM_001079872
基因名称: CUL4B
基因别名: SFM2; MRXSC; MRXHF2; MRXS15
基因描述: Homo sapiens cullin 4B (CUL4B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2688 (查看编码区序列)
翻译后氨基酸长度: 895 (查看氨基酸序列)
Transcript Variant: This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter and unique N-terminus, compared to isoform 1.
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G104532 人 CUL4B (NM_001079872) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]