人 CUL7 (NM_014780) cDNA克隆

Accession: NM_014780
基因名称: CUL7
基因别名: KIAA0076; dJ20C7.5
基因描述: Homo sapiens cullin 7 (CUL7), transcript variant 2, mRNA.
种属: Human
CDS区长度: 5097 (查看编码区序列)
翻译后氨基酸长度: 1698 (查看氨基酸序列)
Transcript Variant: This variant (2) uses alternate splice junctions at the 3' end of two different exons compared to variant 1. One alternate splice junction causes a frameshift compared to variant 1 while the other does not. The resulting isoform (2) has a longer N-terminus and contains an alternate segment compared to isoform 1.
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G118163 人 CUL7 (NM_014780) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]