人 MAP4 (NM_002375) cDNA克隆

Accession: NM_002375
基因名称: MAP4
基因描述: Homo sapiens microtubule-associated protein 4 (MAP4), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3459 (查看编码区序列)
翻译后氨基酸长度: 1152 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript. It encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G104633 人 MAP4 (NM_002375) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]