人 MAP4 (NM_001134364) cDNA克隆

Accession: NM_001134364
基因名称: MAP4
基因描述: Homo sapiens microtubule-associated protein 4 (MAP4), transcript variant 4, mRNA.
种属: Human
CDS区长度: 3408 (查看编码区序列)
翻译后氨基酸长度: 1135 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate exon and uses an alternate splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 4) has a shorter and distinct C-terminus, compared to isoform 1.
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G104635 人 MAP4 (NM_001134364) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]