人 SULF2 (NM_018837) cDNA克隆

Accession: NM_018837
基因名称: SULF2
基因别名: HSULF-2
基因描述: Homo sapiens sulfatase 2 (SULF2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2613 (查看编码区序列)
翻译后氨基酸长度: 870 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (a). Both variants 1 and 3 encode the same isoform.
产品编号 产品名称 载体 规格 价格
G105002 人 SULF2 (NM_018837) cDNA克隆 pDONR223 2ug质粒 点击询价

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]