人 SULF1 (NM_001128205) cDNA克隆

Accession: NM_001128205
基因名称: SULF1
基因别名: SULF-1; HSULF-1
基因描述: Homo sapiens sulfatase 1 (SULF1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2616 (查看编码区序列)
翻译后氨基酸长度: 871 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript. Variants 1-4 encode the same protein.
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G120204 人 SULF1 (NM_001128205) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]