人 WDR33 (NM_001006622) cDNA克隆

Accession: NM_001006622
基因名称: WDR33
基因别名: NET14; WDC146
基因描述: Homo sapiens WD repeat domain 33 (WDR33), transcript variant 2, mRNA.
种属: Human
CDS区长度: 981 (查看编码区序列)
翻译后氨基酸长度: 326 (查看氨基酸序列)
Transcript Variant: This variant (2) represents the shortest transcript. It lacks multiple 3' exons but has an alternate 3' segment, as compared to variant 1. The encoded isoform 2 has a shorter and distinct C-terminus, has only two WD repeats, and lacks the collagen-like and GPR domains, compared to isoform 1.
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G105839 人 WDR33 (NM_001006622) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]