人 SETMAR (NM_001243723) cDNA克隆

基本信息

Accession: NM_001243723
基因名称: SETMAR
基因别名: Mar1; HsMar1; METNASE
基因描述: Homo sapiens SET domain and mariner transposase fusion gene (SETMAR), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1638 (查看编码区序列)
翻译后氨基酸长度: 545 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G106105 人 SETMAR (NM_001243723) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SETMAR (NM_006515) cDNA克隆 transcript variant 1
人 SETMAR (NM_001243723) cDNA克隆 transcript variant 2
人 SETMAR (NM_001276325) cDNA克隆 transcript variant 4

基因简介

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

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