人 CHST11 (NM_001173982) cDNA克隆

基本信息

Accession: NM_001173982
基因名称: CHST11
基因别名: C4ST; C4ST1; C4ST-1; HSA269537
基因描述: Homo sapiens carbohydrate (chondroitin 4) sulfotransferase 11 (CHST11), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1044 (查看编码区序列)
翻译后氨基酸长度: 347 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame donor splice site at the 5' terminal exon compared to variant 1. This results in a shorter isoform (2) missing a 5 aa protein segment near the N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G106107 人 CHST11 (NM_001173982) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CHST11 (NM_018413) cDNA克隆 transcript variant 1
人 CHST11 (NM_001173982) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

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