人 CHST12 (NM_001243794) cDNA克隆

Accession: NM_001243794
基因名称: CHST12
基因别名: C4S-2; C4ST2; C4ST-2
基因描述: Homo sapiens carbohydrate (chondroitin 4) sulfotransferase 12 (CHST12), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1245 (查看编码区序列)
翻译后氨基酸长度: 414 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the predominant transcript. Variants 1-3 encode the same protein.
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G110816 人 CHST12 (NM_001243794) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene. [provided by RefSeq, Aug 2011]