人 RASSF8 (NM_001164746) cDNA克隆

Accession: NM_001164746
基因名称: RASSF8
基因别名: HOJ1; C12orf2
基因描述: Homo sapiens Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 (RASSF8), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1260 (查看编码区序列)
翻译后氨基酸长度: 419 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1, 2 and 3 encode the same isoform.
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G106424 人 RASSF8 (NM_001164746) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]