人 RASSF5 (NM_182664) cDNA克隆

基本信息

Accession: NM_182664
基因名称: RASSF5
基因别名: RAPL; Maxp1; NORE1; NORE1A; NORE1B; RASSF3
基因描述: Homo sapiens Ras association (RalGDS/AF-6) domain family member 5 (RASSF5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1011 (查看编码区序列)
翻译后氨基酸长度: 336 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, compared to variant 1, that causes a frameshift. The resulting protein (isoform B) is shorter and has a distinct C-terminus, compared to isoform A.

订购信息

产品编号 产品名称 载体 规格 价格
G115994 人 RASSF5 (NM_182664) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RASSF5 (NM_182663) cDNA克隆 transcript variant 1
人 RASSF5 (NM_182664) cDNA克隆 transcript variant 2
人 RASSF5 (NM_182665) cDNA克隆 transcript variant 3

基因简介

This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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