人 GRB7 (NM_005310) cDNA克隆

Accession: NM_005310
基因名称: GRB7
基因描述: Homo sapiens growth factor receptor-bound protein 7 (GRB7), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1599 (查看编码区序列)
翻译后氨基酸长度: 532 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR and coding sequence compared to variant 4. The resulting isoform (a) is shorter at the N-terminus compared to isoform b. Variants 1, 2, and 3 all encode the same isoform (a).
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G106971 人 GRB7 (NM_005310) cDNA克隆 pDONR223 2ug质粒 点击询价

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]