人 ALOX15B (NM_001141) cDNA克隆

Accession: NM_001141
基因名称: ALOX15B
基因别名: 15-LOX-2
基因描述: Homo sapiens arachidonate 15-lipoxygenase, type B (ALOX15B), transcript variant d, mRNA.
种属: Human
CDS区长度: 2031 (查看编码区序列)
翻译后氨基酸长度: 676 (查看氨基酸序列)
Transcript Variant: This variant (d) represents the longest transcript and encodes the longest isoform (d).
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G107211 人 ALOX15B (NM_001141) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]