人 SIGMAR1 (NM_005866) cDNA克隆

Accession: NM_005866
基因名称: SIGMAR1
基因别名: SRBP; ALS16; OPRS1; SR-BP; SIG-1R; SR-BP1; sigma1R; hSigmaR1
基因描述: Homo sapiens sigma non-opioid intracellular receptor 1 (SIGMAR1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 672 (查看编码区序列)
翻译后氨基酸长度: 223 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G108291 人 SIGMAR1 (NM_005866) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013]