人 KCNIP3 (NM_013434) cDNA克隆

Accession: NM_013434
基因名称: KCNIP3
基因别名: CSEN; DREAM; KCHIP3
基因描述: Homo sapiens Kv channel interacting protein 3, calsenilin (KCNIP3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 771 (查看编码区序列)
翻译后氨基酸长度: 256 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G108690 人 KCNIP3 (NM_013434) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]