人 LIG3 (NM_002311) cDNA克隆

基本信息

Accession: NM_002311
基因名称: LIG3
基因别名: LIG2
基因描述: Homo sapiens ligase III, DNA, ATP-dependent (LIG3), transcript variant beta, mRNA.
种属: Human
CDS区长度: 2850 (查看编码区序列)
翻译后氨基酸长度: 949 (查看氨基酸序列)
Transcript Variant: This variant (beta) contains an alternate in-frame exon in the coding region which includes an in-frame stop codon, compared to variant alpha. This isoform (beta) is shorter and has a distinct C-terminus, compared to isoform alpha.

订购信息

产品编号 产品名称 载体 规格 价格
G109301 人 LIG3 (NM_002311) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 LIG3 (NM_013975) cDNA克隆 transcript variant alpha
人 LIG3 (NM_002311) cDNA克隆 transcript variant beta

基因简介

This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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