人 LIG3 (NM_013975) cDNA克隆

Accession: NM_013975
基因名称: LIG3
基因别名: LIG2
基因描述: Homo sapiens ligase III, DNA, ATP-dependent (LIG3), transcript variant alpha, mRNA.
种属: Human
CDS区长度: 3030 (查看编码区序列)
翻译后氨基酸长度: 1009 (查看氨基酸序列)
Transcript Variant: This variant (alpha) represents the longer transcript and encodes the longer isoform (alpha).
产品编号 产品名称 载体 规格 价格
G109302 人 LIG3 (NM_013975) cDNA克隆 pDONR223 2ug质粒 点击询价
人 LIG3 (NM_013975) cDNA克隆 transcript variant alpha
人 LIG3 (NM_002311) cDNA克隆 transcript variant beta

This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]