人 FCGR2B (NM_001002273) cDNA克隆

基本信息

Accession: NM_001002273
基因名称: FCGR2B
基因别名: CD32; FCG2; CD32B; FCGR2; IGFR2
基因描述: Homo sapiens Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 873 (查看编码区序列)
翻译后氨基酸长度: 290 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon and uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G109511 人 FCGR2B (NM_001002273) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 FCGR2B (NM_004001) cDNA克隆 transcript variant 1
人 FCGR2B (NM_001002273) cDNA克隆 transcript variant 2
人 FCGR2B (NM_001002274) cDNA克隆 transcript variant 3
人 FCGR2B (NM_001002275) cDNA克隆 transcript variant 4
人 FCGR2B (NM_001190828) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

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